Santana is a surname with origins in Spain and Portugal, derived from the Latin name Sanctus, meaning “holy” or “saint”. It is a fairly common surname and can be found throughout the world, particularly in Latin America where it is often associated with the famous Latin rock band, Santana. The name has also been adopted by other musical artists and performers as a stage name. Santana is a name that carries a sense of spirituality and reverence, reflecting the deep cultural roots and traditions of its origin.