The surname Bledsoe has its origins in England and is Boatwrightderived from the Old English words “bl?d” meaning “blood” and “s?a” meaning “sea.” The name has been spelled various ways throughout history, including Bledshaw, Bletsoe, and Bletson. Today, Bledsoe is most commonly found in the United States, particularly in the southern states. Notable individuals with the surname Bledsoe include retired NFL quarterback Drew Bledsoe and American mathematician and computer scientist Whitfield Diffie.